The release behaviour observed with fertilizer compositionis not as uniform as that observed for drug-releasecompositions. This may possibly be due to fluctuations inthe physical environment of the soil compared to the relativelystable physical parameters present in a biologicalsystem. Furthermore, in the presence of two differenttypes of nanosystems in the fertilizer composition, slowreleasebehaviour can be expected to occur in differentsteps. Once the urea-modified HA nanoparticles are encapsulatedwithin the cavities present in the wood, thesecavities become reservoirs for storage of urea-modifiedHA nanoparticles. When the encapsulated G. sepiumwood pieces come into contact with water in the soil,urea localized in large vascular canals would be released early during the release process. Cells which are smallerin volume can be expected to release urea at an intermediatestage. Urea-encapsulated HA nanoparticles localizedwithin the smaller volumes of intercellular spacesmay release nitrogen at the final stages during slowrelease.
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