* (3) *In both types of diabetes, this normal process malfunctions. A gland called the pancreas, found just behind the stomach, makes insulin. In patients with insulin-dependent diabetes, the pancreas does not produce insulin at all. This condition usually begins in childhood and is known as Type I (formerly called juvenile-onset) diabetes. These patients must have daily insulin injections to survive. People with non-insulin-dependent diabetes usually produce some insulin in their pancreas, but the body's tissues do not respond very well to the insulin signal and therefore do not metabolize the glucose properly—a condition known as insulin resistance.*
(4) *Insulin resistance is an important factor in non-insulin-dependent diabetes, and scientists are researching the causes of insulin resistance. They have identified two possibilities. The first is that there could be a defect in the insulin receptors on cells. Like an appliance that needs to be plugged into an electrical outlet, insulin has to bind to a receptor in order to function. Several things can go wrong with receptors. For example, there may not be enough receptors for insulin to bind to, or a defect in the receptors may prevent insulin from binding. The second possible cause of insulin resistance is that, although insulin may bind to the receptors, the cells may not read the signal to metabolize the glucose. Scientists continue to study these cells to see why this might happen.*
(5) *There is no cure for diabetes yet. However, there are ways to alleviate its symptoms. In 1986, a National Institutes of Health panel of experts recommended that the best treatment for non-insulin-dependent diabetes is a diet that helps one maintain a normal weight and pays particular attention to a proper balance of the different food groups. Many experts, including those in the American Diabetes Association, recommend that 50 to 60 percent of daily calories come from carbohydrates, 12 to 20 percent from protein, and no more than 30 percent from fat. Foods that are rich in carbohydrates, such as breads, cereals, fruits, and vegetables, break down into glucose during digestion, causing blood glucose to rise. Additionally, studies have shown that cooked foods raise blood glucose higher than raw, unpeeled foods. A doctor or nutritionist should always be consulted for more information and for help in planning a diet to offset the effects of this form of diabetes.
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