Mature ECs are terminally differentiated and quiescent, which limits their capacity to repair damagedendothelium [45]. On the other hand, circulatingEPCs, expressing CD133+, CD34+, VEGFR2+, CD14−,VE-cadherin−, eNOS−, are capable of adhering to nonendothelialized intravascular surfaces, differentiatinginto ECs, and forming a functional endothelium [34,45–48].
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