Twenty-eight healthy subjects (21 female) were studied at the Vanderbilt Autonomic Dysfunction Center in Nash- deficiency, folate deficiency, and many other conditions. Although determination of Hct seems reproducible and straightforward under controlled laboratory conditions, it is a far more complicated index of erythrocyte status than is commonly appreciated. Many factors can influence the value obtained for Hct in a clinical setting. These factors are usually pathological, although some may be due to normal physiological circumstances.
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