The nuances of the association between lipoprotein complexes and calcific AS are discussed in detail by Rogers and Aikawa6 who suggest that ‘Clinical studies assessing the effectiveness of Lp(a) or ApoCIII antisense oligonucleotides, EO6 antibodies or other means of targeting these apolipoproteins and oxidised lipids could be the next major therapeutic step to identify non- surgical interventions for calcific aortic valve disease, particularly in the high- risk population of patients with elevated Lp(a).’(figure 4) A comprehensive statement from the British Association for Cardiovascular Prevention and Rehabilitation (BACPR) provides a summary and recommendations for optimal nutritional strategies for primary and secondary prevention of CVD.7 They recommend switching the focus from macronutrients (protein, carbohydrate, etc) to whole foods (fruits, vegetables, eggs, meat, etc) when providing dietary advice to patients. Both healthcare providers and patients will appreciate the clear, concise and practical advice in this detailed document.
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