A new "old" disease
Prior unsolved outbreaks in the 1950s and 1960s
U id tifi d i i l t d f ti t’ bl d Unidentified organism isolated from a patient’s blood
in 1947: Legionella Bozemani many years later
USA:
8,000 ‐ 18,000/yr get some form of Legionnaires' disease
Australia:
1/3 rd of the population has antibodies against Legionella
Legionnaires’ disease: historical perspective. Clin Microbiol Rev. 1988 Jan 1;1:60‐81
The organism
Fastidious gram‐negative bacillus
>50 species of the family Legionellaceae >50 species of the family Legionellaceae
L. pneumophila:
90% of human infections
L. micdadi and L. dunoffi:
2 nd and 3 rd most common species to cause LD in 2 and 3 most common species to cause LD in
children
Distribution of Legionella species and serogroups isolated by culture
in patients with sporadic community‐acquired legionellosis: an
international collaborative survey. J Infect Dis. 2002 Jul 1;
186(1):127‐8.
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