Group separations: the components of a sample are separated into two major groupsaccording to size range. A group separation can be used to remove high or low molecularweight contaminants (such as phenol red from culture fluids) or for desalting and bufferexchange.2. High resolution fractionation of biomolecules: the components of a sample are separatedaccording to differences in their molecular size. High resolution fractionation can be usedto isolate one or more components, to separate monomers from aggregates, or to performa molecular weight distribution analysis
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