Figure 2. Taxol biosynthetic pathway. ggpps: geranylgeranyl diphosphate synthase; ts: taxadiene synthase;h-5: cytochrome P450 taxadiene 5-hydroxylase; tat: taxa-4(20), 11(12)-dien-5a-ol-O-acetyltransferase; h-10: cytochrome P450 taxane 10-hydroxylase; tbt: taxane 2a-O-benzoyltransferase; dbat: 10-deacetylbaccatin III-10-O-acetyltransferase. Multiple arrows indicate several as yet undefined steps.
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