Saliva CollectionSaliva samples were obtained at one point beforechemoradiotherapy and at three points during thetreatment (7th, 21st, and 35th sessions of RT) accordingto the spitting method proposed by Navazesh [24]. Patientscould not eat or drink an hour before saliva collectionprocedure. They washed the mouth with pure water andswallowed whole saliva before collection.For unstimulated saliva collection, patients were instructedto slightly tilt their head down and then theyshould expectorate the saliva, which was produced over a
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