Electrostatic interactions are known to play a crucial role in protein structure and function (Roy and Taraphder, 2007). Electrostatic interactions are collectively known as Van der Waals forces and include dipole-dipole interactions, London dispersion forces, and hydrogen-bonding. These forces are less than 1/6 as strong as covalent or ionic bonds (Cramp, 2007). Estimation of electrostatic bonds is the heart of any theoretical modeling of proteins. The electrostatic interaction between proteins or peptides can be reduced by addition of 0.3M NaCl; the counter- ions of NaCl interrupt electrostatic interactions leading to the breakdown of electrostatic bonds (Damianou and Kiosseoglou, 2006; Zhong et al., 2006).
đang được dịch, vui lòng đợi..
