A 4-month-old infant is evaluated by a dermatologist because of thick, erythematous skin with fine scaling, principally involving his face. The mother reports that the infant is "always scratching his face:' An older brother and a maternal uncle had a similar condition. Screening hematologic studies show the following:
Erythrocyte count 5.1 million/mm3
Leukocyte count 12,000/mm3
Segmented neutrophils 80%
Bands 5%
Eosinophils 3%
Basophils 1%
Lymphocytes 5%
Monocytes 6%
Platelet count 35,000/mm" with the comment that the platelets are smaller than normal
Serum immunoglobulin studies demonstrate the following:
IgA 120 mgldL
IgE 2300 IU/mL
IgG 900 mgldL
IgM 15 mg/dL
Patients with this condition have a significantly increased incidence of which of the following?
(A) Basal cell carcinoma
(B) Hodgkin lymphoma
(C) Melanoma
(D) Non-Hodgkin lymphoma
(E) Squamous cell carcinoma of the skin.