Tetralogy of Fallot (TOF)TOF is the most common cause of CCHD. It’s actually a combination of four different defects. That’s why it’s called “tetralogy” (meaning four) of Fallot. TOF includes a hole between the right and left ventricles of the heart, a narrow pulmonary valve, a thickening of the right ventricle muscles, and a misplaced aortic valve. The defects lead to blood with oxygen and blood without oxygen getting mixed together and pumped throughout the body.
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