Stearic acid and Gliadins, hydroxypropyl methyl cellulose phthalate, have also been used for preparation of NPs. Apart from ‘‘drug only’’ and polymeric forms, NPs are also prepared by utilizing simple organic or inorganic compounds (62–64).The choice of biodegradable polymers on offer is limited. Tyner et al. (65) converted the drug camptothecin into micelles with the help of a negatively charged surfactant and these micelles were then encapsulated into NPs of magnesium–aluminum layered double hydroxides by an ion exchange process.Stacked sheet-like nanostructures of 500nm in two dimen-sions and 10nm in the third dimension were obtained.
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