1. Introduction The incidence of early pregnancy failure is high in humans, estimated to be 30% prior to conceptus implantation and 30% before 6 weeks of pregnancy [1]. Uncontrolled reactive oxygen species (ROS) production by antioxidants can result in oxidative damage to cellular macromolecules, including lipids, proteins and nucleic acids, and consequently leads to lipid peroxidation, protein degradation and DNA lesions [2] that adversely affect prenatal developmental outcome [3,4]. ROS- induced oxidative stress has been reported to be involved in a number of pregnancy disorders such as abortion, intra-uterine growth restriction (IUGR) of foetus and prenatal mortality [5,6].
đang được dịch, vui lòng đợi..
