Figure 4 Amino acid sequence alignment of group I and group II glucose isomerases. For abbreviations and references see Table 4. Group I and group II sequences werealigned as separate groups using the Multiple Alignment Tool from PIR at http://www.nbrf.georgetown.edu.pirwww/search/multaln.html which makes use of ClustalW.Subsequently, sequences 8–12 from group I and 13–18 from group II were aligned in order to establish the alignment between the two groups. Residues that are highlyconserved in group I (and also found in group II) are indicated by white letters and a black background. Residues that are highly conserved in group II (and also found ingroup I) are indicated by black letters and a gray background.
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