• The cat’s body temperature remain

• The cat’s body temperature remained between 40 °C and 42 °C for more than 48 h.

• The cat’s body temperature dropped below 37 °C.

• The cat’s PCV dropped below 25 %.
• The parasitaemia remained static, but the PCV continued decreasing.

RESULTS

None of the cats showed an elevated temperature at any stage.
Blood smears from recipients of donor cat 2 (1 from Group I; Groups V and VI) re-mained negative until Day 4 post-infection. Parasitaemia

Kết quả (Việt) 1:

• The cat’s body temperature remained between 40 °C and 42 °C for more than 48 h.• The cat’s body temperature dropped below 37 °C.• The cat’s PCV dropped below 25 %.• The parasitaemia remained static, but the PCV continued decreasing.RESULTSNone of the cats showed an elevated temperature at any stage.Blood smears from recipients of donor cat 2 (1 from Group I; Groups V and VI) re-mained negative until Day 4 post-infection. Parasitaemia <0.1 % was discernible from Day 5 until Days 7 to 12, after which it increased rapidly. Blood smears made from 4 recipients of donor cat 1 (2 from Group I; Group II) showed parasitaemia <0.1 % on Day 1 post- On Day 0, cats housed at OVARU (2 from Group I; Groups II, III and IV) were inoculated intravenously with 2 m in-fected blood from donor cat 1. Cats housed at PS-OVI (1 from Group I; Groups V and VI) were inoculated intra-venously with 2 m infected blood from donor cat 2. Body temperature, and blood smears made by collecting a drop of blood from the tip of the tail, were examined and recorded daily. Blood smears were examined and percentage parasitised Fig. 1: Parasitaemia and PCV of 3 cats treated with primaquine phosphate. The treatment regimen (Table 1) was initiated on Day 18 for cat 1 and on Day 15 for cats 2 and 3. 54 0038-2809 Tydskr.S.Afr.vet.Ver. (2000) 71(1): 53–57 Fig. 2: Parasitaemia and PCV of 2 cats treated with buparvaquone. The treatment regimen (Table 1) was initiated on Day 15 for both cats. Treatment with primaquine phosphate com-menced on Day 18 for cat 1 and Day 19 for cat 2.Fig. 3: Parasitaemia and PCV of 2 cats treated with rifampicin. The treatment regimen (Table 1) was initiated on Day 15 for both cats. Treatment with primaquine phosphate commenced on Day 20 for cat 1 and Day 22 for cat 2. Cat 2 was euthanased on Day 28.infection; blood smears made of the re- mained <0.1 % until Days 7 to 10, aftermaining 4 cats (Groups III and IV) were which it increased rapidly.negative on Day 1, but demonstrated Parasitaemia and PCV of cats on differ-parasitaemia <0.1 % from Day 2 onward. ent treatment regimens were as follows:Parasitaemia of all these recipients re- Fig. 1 (Group I, primaquine), Fig. 2 (Group Fig. 4: Parasitaemia and PCV of 2 cats treated with sulphadiazine-trimethoprim. The treat-ment regimen (Table 1) was initiated on Day 15 for both cats. Treatment with primaquine phosphate commenced on Day 21 for cat 1 and Day 22 for cat 2.0038-2809 Jl S.Afr.vet.Ass. (2000) 71(1): 53–57 II, buparvaquone), Fig. 3 (Group III, rifampicin), Fig . 4 (Group IV, sulphadiazine-trimethoprim), Fig. 5 (Group V, enrofloxacin) and Fig. 6 (Group VI, danofloxacin).DISCUSSIONThe absence of a temperature reaction agrees with results of previous studies9,18.The prepatent periods reported here (1 to 5 days) are similar to results reported previously: Potgieter18 found prepatent periods of 3 to 28 days, while Futter & Belonje9 found parasites on blood smears within 24 to 48 hours post infection.The differences in prepatent periods in cats housed at OVARU and PS-OVI, respectively, may be attributable to differ-ences in inocula and/or recipients. Although the 2 donor cats had been in-fected with the same B. felis isolate and the parasitaemias of inocula were similar, one cannot assume that they were identical. The recipients housed at PS-OVI had been held in familiar surroundings for a few months, while those at OVARU had been in residence for 14 days only, and may still have been stressed and thus more susceptible to infection. In all cats, however, parasitaemias increased to levels high enough for drug screening.The anti-babesial action of primaquine found in this study confirmed the results reported by Potgieter18. Primaquine had a dramatic effect on parasitaemia, particu-larly in control cats 2 and 3 (Fig. 1). Primaquine failed to sterilise the infec-tions, however: 2 of the cats still yielded parasites on blood smear examination 12 months after conclusion of the trial.Trong 2 ngày sau khi chính quyền buparvaquone 1, nó xuất hiện như nếu thuốc đã có tương tự như babesial chống phù hợp-quan hệ primaquine. Ngày thứ 3, khi điều trị 2 được quản lý, parasitaemia trong cả hai mèo bắt đầu tăng lên nhanh chóng, tăng đến mức như vậy rằng họ đã được gỡ bỏ từ các phiên tòa. Sau khi điều trị với primaquine, PVC cả mèo đã c. 48 h còn phục hồi hơn tha