ScombrotoxinScombroid intoxication, sometimes referred to as histamine poisoning, results from eating fish that have been incorrectly chilled after harvesting. Scombrotoxin is attributed mainly to Enterobacteriaceae, which can produce high levels of histamine and other biogenic amines in the fish muscle when products are not immediately chilled after catching. The main susceptible fish are the scombroids such as tuna, mackerel, and bonito, although it can be found in other fish families such as Clupeidae. The intoxication is rarely fatal and symptoms are usually mild. Rapid refrigeration after catching and a high standard of handling during processing should prevent the development of the toxin. The toxin is not inactivated by normal heat processing. In addition, fish may contain toxic levels of histamine without exhibiting any of the usual sensory parameters characteristic of spoilage.
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